Champix vs. Zyban
Champix pills and Zyban are the two latest prescription medicines which help people in smoking cessation.
Champix pills help in all-round treatment by reducing nicotine cravings and withdrawal effects associated with smoking cessation. Champix pills also work by blocking the receptors in the brain that are linked to nicotine addiction.
Zyban is principally an antidepressant which was later approved as smoking cessation medicine after reports of smoking cessation effects with Zyban started flowing in. However, the theory behind its smoking cessation effects is not yet determined.
It has been found in several clinical trials, Champix pills are way better than quitting smoking the cold turkey way or with Zyban.
Although both Zyban and Champix pills work for the same cause, there is a vast difference between the two medications. Here are few major differences between Zyban and Champix pills:
Champix vs. Zyban in detail
Manufacturer
The manufacturer of Champix pills is Pfizer whereas Zyban is manufactured by GlaxoSmithKline
Usage
Champix pills are specifically meant for smoking cessation. Zyban is an aid to smoking cessation treatment.
Date of Approval
Champix pills were approved by European Commission in October 2006 and by FDA in May 2006 as Chantix. Zyban was approved for marketing in the UK in June 2000 and by FDA in May 1997.
Treatment
Champix pills help in reducing nicotine cravings and withdrawal effects associated with smoking cessation. Zyban was designed initially for treating a condition called major depressive disorder but was later found to have smoking cessation benefits too.
Working
Champix pills work by blocking the nicotine receptors in the brain that cause addiction and in this way help in smoking cessation. The mechanism and reason behind anti-smoking properties of Zyban is not yet established.
Active Ingredient
The active ingredient in Champix pills is 'Varenicline Tartrate'. The active ingredient in Zyban is 'Bupropion Hydrochloride'.
Success Rate in Clinical Trials
Champix pills in 12 week clinical trials showed success rate of 44% in smoking cessation and a further one year study showed 22% abstinence.
In a 12 week study, it was found that the smoking cessation success rate of Zyban was 29.5 % and in a year's study the abstinence rate was found to be 16%.
Dosage
Champix pills dosage of 1 mg. twice a day is more effective than any other smoking cessation medicine dosage.
Zyban dosage of 150 mg. twice daily works better than placebo but is less effective than Champix pills.
Contraindication
Champix pills are not recommended in combination with any other smoking cessation medicines. Combination treatment of Zyban and other nicotine replacement therapies is often prescribed for smoking cessation.
Buy Champix pills, "the difference between a successful person and others is not lack of strength, not lack of help, but rather lack of will." Have an iron will power and you can quit smoking with Champix pills!
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